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- She made a splash both onscreen and off with her first film, Go Fish. In addition to starring in the landmark lesbian indie, she co-wrote the screenplay with her then-girlfriend Rose Troche, who directed it.
- Following Go Fish, she wrote or co-wrote the scripts for American Psycho, The Notorious Bettie Page and BloodRayne.
- As well as a small part in American Psycho, she has starred in The Watermelon Woman, Preaching to the Perverted and Itty Bitty Titty Committee.
- She also has appeared in cameo roles in several GLBT-themed films, such as Chasing Amy, Kiss Me, Guido and The Fluffer, plus voiced a character in the original Rick & Steve the Happiest Gay Couple in All the World short.
- For television, she was a writer and story editor for the first two seasons of The L Word, as well as appearing as Gabby Deveaux in several episodes of the groundbreaking series.
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